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Table 5 Most frequent (≥5% of patients) grade 3–4 treatment-emergent adverse events (TEAEs)

From: Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens

Preferred term

Azacitidine (n = 128) n (%)

CCR (n = 130) n (%)

Any grade 3–4 TEAE

111 (87)

113 (87)

Thrombocytopenia

33 (26)

27 (21)

Febrile neutropenia

29 (23)

43 (33)

Neutropenia

28 (22)

25 (19)

AML*

25 (20)

23 (18)

Pneumonia

24 (19)

18 (14)

Anaemia

19 (15)

21 (16)

Pyrexia

13 (10)

9 (7)

Hypokalaemia

9 (7)

10 (8)

Leukopenia

8 (6)

10 (8)

Sepsis

7 (6)

9 (7)

Decreased appetite

6 (5)

2 (2)

Dyspnoea

6 (5)

4 (3)

  1. Safety-evaluable patients received at least 1 dose of study drug and had at least 1 post-baseline safety assessment. Patients who received BSC only were included in safety assessments if they had at least 1 post-randomisation safety assessment
  2. *Worsening disease