Table 1 EpCAM expression pattern, including staining distribution, staining intensity, and percentage of EpCAM positive cells, in SCC, HSIL, and LSIL of the uterine cervix
| Â | Specimen group | r | p-value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
SCC (n = 44) | HSIL (n = 43) | LSIL (n = 48) | Normal (n = 54) | |||||||
n | (%) | n | (%) | n | (%) | n | (%) | |||
Staining distribution | ||||||||||
 Full thickness | 39 | (88.6%) | 29 | (67.4%) | 4 | (8.3%) | 0 | (0%) | 0.890 | <0.001 |
 Up to 2/3 of epithelium | 5 | (11.4%) | 13 | (30.2%) | 10 | (20.8%) | 0 | (0%) |  |  |
 Up to 1/3 of epithelium | 0 | (0%) | 1 | (2.3%) | 32 | (66.7%) | 4 | (7.4%) |  |  |
 Basal layer | 0 | (0%) | 0 | (0%) | 1 | (2.1%) | 50 | (92.6%) |  |  |
 No staining | 0 | (0%) | 0 | (0%) | 1 | (2.1%) | 0 | (0%) |  |  |
Staining intensity | ||||||||||
 Intense | 29 | (65.9%) | 23 | (53.5%) | 0 | (0%) | 1 | (1.9%) | 0.698 | <0.001 |
 Moderate | 14 | (31.8%) | 17 | (39.5%) | 29 | (60.4%) | 15 | (27.8%) |  |  |
 Weak | 1 | (2.3%) | 3 | (7.0%) | 18 | (37.5%) | 38 | (70.4%) |  |  |
 No staining | 0 | (0%) | 0 | (0%) | 1 | (2.1%) | 0 | (0%) |  |  |
% of EpCAM positive cells | ||||||||||
 71–100% | 38 | (86.4%) | 38 | (88.4%) | 21 | (43.8%) | 21 | (38.9%) | 0.436 | <0.001 |
 41–70% | 5 | (11.4%) | 5 | (11.6%) | 22 | (45.8%) | 25 | (46.3%) |  |  |
 11–40% | 1 | (2.3%) | 0 | (0%) | 4 | (8.3%) | 8 | (14.8%) |  |  |
 0–10% | 0 | (0%) | 0 | (0%) | 1 | (2.1%) | 0 | (0%) |  |  |