Table 3 Sensitivity and specificity between HPV DNA detection by PCR (“positive result defined as disease for statistical testing”) and p16 by IHC
From: Prevalence and types of high-risk human papillomaviruses in head and neck cancers from Bangladesh
Point estimate | Confidence limits (95% CI) | |
|---|---|---|
Types | Value | Lower, upper |
Sensitivity | 72.22% | 54.81% to 85.80% |
Specificity | 98.55% | 94.86% to 99.82% |
Positive Likelihood Ratio | 49.83 | 12.40 to 200.21 |
Negative Likelihood Ratio | 0.28 | 0.17 to 0.48 |
“Disease” prevalence | 20.69% (a) | 14.93% to 27.47% |
Positive Predictive Value | 92.86% (a) | 76.50% to 99.12% |
Negative Predictive Value | 93.15% (a) | 87.76% to 96.67% |