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Table 1 Demographic and clinical characteristics of patients

From: Prevalence and types of high-risk human papillomaviruses in head and neck cancers from Bangladesh

Characteristics All patients (n = 174) (%) HPV DNA + ve (n = 36) (%) HPV DNA-ve (n = 138)(%) X2 (Chi-square) p-value
Mean Age 56.6 54.2 57.2   0.143
Age groups (years)
 20–59 94 (54.1) 26 (72.2) 68 (49.3) 6.053* 0.014
 60 and above 80 (45.9) 10 (27.8) 70 (50.7)   
Gender
 Male 138 (79.3) 30 (83.3) 108 (78.3) 0.448 0.503
 Female 36 (20.7) 6 (16.7) 30 (21.7)   
Primary Tumour sites
 Oral Cavity (C02-C06) 55 (31.6) 11 (30.6) 44 (31.9) 8.412* 0.038
 Oropharynx (C01, C09 & C10) 35 (20.1) 13 (36.1) 22 (15.9)   
 Larynx (C32) 64 (36.8) 8 (22.2) 56 (40.6)   
 Hypopharynx (C13) 20 (11.5) 4 (11.1) 16 (11.6)   
Histopathological Grading
 Well differentiated 48 (27.6) 4 (11.1) 44 (31.9) 8.947* 0.011
 Moderately differentiated 92 (52.9) 20 (55.6) 72 (52.2)   
 Poorly differentiated 34 (19.5) 12 (33.3) 22 (15.9)   
Immunohistochemistry (IHC) Analysis
p16 expression
 Positive 28 (16.1) 26 (72.2) 2 (1.4) 105.914* 0.0001
 Negative 146 (83.9) 10 (27.8) 136 (98.6)   
p53 expression
 Positive 86 (49.4) 23 (63.9) 63 (45.7) 3.799 0.051
 Negative 88 (51.6) 13 (36.1) 75 (54.3)   
Cyclin D1 expression
 Positive 62 (35.6) 13 (36.1) 49 (35.5) 0.05 0.946
 Negative 112 (64.4) 23 (63.9) 89 (64.5)   
pRb expression
 Positive 66 (37.9) 15 (41.7) 51 (37.0) 0.269 0.604
 Negative 108 (62.1) 21 (58.3) 87 (63.0)   
  1. *indicates statistical significance