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Table 2 Correlation of toxicity with the maximum point dose delivered at the OAR and the institutional constraints

From: Stereotactic body radiotherapy (SBRT) for locally advanced intrahepatic and extrahepatic cholangiocarcinoma

Toxicity

Nr of Fractions

OAR

Dmax (Gy) delivered

EQD23 (Gy) delivered

Dmax constraint (Gy) for the OAR

EQD23 (Gy) constraint

Gastric bleeding

12

stomach

45.6

62

47.4

65.8

GI bleeding

12

stomach

39.4

49.5

47.4

65.8

Duodenal ulceration

10

duodenum

25

27.5

44.3

65.8

  1. OAR organ at risk, EQD2 3 equieffective doses in 2 Gy (α/β = 3), GI gastro-intestinal, Dmax maximum point dose