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Table 1 DLBCL patients’ characteristics and correlations with TP53 SNP rs1042522

From: TP53 Arg72 as a favorable prognostic factor for Chinese diffuse large B-cell lymphoma patients treated with CHOP

Clinical parameters No. Genotype P Clinical parameters No. Genotype P
GG + GC CC GG + GC CC
Gender      β2-MG     
 Male 175 147 28 0.213  Positive 109 79 30 0.004
 Female 250 198 52  Negative 277 236 41
Age      LDH     
 ≤60 269 216 53 0.543  Positive 192 155 37 0.83
 >60 156 129 27  Negative 233 190 43
Stage      ESR     
 I-II 182 146 36 0.662  Positive 230 185 45 0.501
 III-IV 243 199 44  Negative 143 119 24
IPI score      ECOG score     
 0–2 289 231 58 0.338  0–2 368 296 72 0.32
 3–5 136 114 22  3–4 57 49 8
Subtype      HBV infection     
 GCB 112 92 20 0.709  Positive 200 159 41 0.355
 Non-GCB 251 202 49  Negative 218 181 37
B symptoms      Treatment     
 Positive 234 200 34 0.012  CHOP/CHOP-like 136 107 29  
 Negative 191 145 46  R-CHOP 289 238 51 0.366
  1. IPI International prognostic index, GCB Gernminal center B cell subtype, MG Microglobulin, LDH Lactate dehydrogenase, ESR Erythrocyte sedimentation rate, ECOG Eastern cooperative oncology group, HBV Hepatitis B virus