Table 1 Patient characteristics (n = 145)
Variable | Value |
|---|---|
Age years, mean (sd) | 76.5 (7.0) |
ECOG performance status, No. (%) (missing = 14) | |
0–1 | 125 (95) |
> 2 | 6 (5) |
Presence of Pain, yes, n (%) | 56 (38.6) |
Brief Pain Inventory Question #3, >2, n (%), (missing =13) | 46 (34.9) |
Baseline PSA, median (range) | 17.4 (0.4 to 2100.0) |
Baseline ALT, median (range) | 20 (8–87) |
Baseline AST, median (range) | 18.5 (6–309) |
Gleason at time of initial diagnosis, n (%) (missing = 4) | |
> 7 | 81 (57.5) |
Local treatment, n (%) | |
None | 58 (40.0) |
External Beam Radiation Therapy | 25 (17.2) |
Radical Prostatectomy | 49 (33.8) |
Both | 13 (8.9) |
Disease location, n (%) (missing =5) | |
Bone only | 75 (53.5) |
Lymph nodes only | 22 (15.7) |
Visceral only | 4 (2.8) |
Prostatic fossa only | 11 (7.8) |
Multiple sites | 28 (20.0) |
Comorbidity, n (%) | |
None | 33 (22.7) |
Cardiovascular only | 50 (35.7) |
Metabolic only | 8 (5.5) |
Multiple (cardiovascular + metabolic) | 26 (17.9) |
Other | 28 (19.3) |
Time to mCRPC from initial diagnosis years, median (range) | 5.0 (0.2 to 17.7) |
Hormonal manipulations before AA >2, n (%) | 22 (15.2) |
Duration of ADT >12 m, n (%) | 113 (77.9) |