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Table 4 Associations between HSV and HPV, and their associations with cervical cancer-NHANES 2003–2010

From: Seropositivity to herpes simplex virus type 2, but not type 1 is associated with cervical cancer: NHANES (1999–2014)

Dependent variable Independent variable aOR (95% CI) P value
HPV16or18a HSV1 1.03 (0.84–1.27) 0.75
HPV16or18a HSV2 2.49 (1.96–3.16) <0.01
Cervical cancera HPV16or18 2.26 (1.14–4.45) 0.02
Cervical cancera HSV2 2.17 (1.28–3.66) 0.00
Cervical cancerb HSV2 1.90 (1.09–3.34) 0.02
  1. Abbreviations: HSV1, herpes simplex virus type 1; HSV2, herpes simplex virus type 2; HPV16or18, human papillomavirus type 16 or 18; aOR, Adjusted odds ratio; CI, confidence interval; NHANES, National Health and Nutrition Examination Survey
  2. aModel was adjusted for age, education, race, poverty income ratio, body mass index, smoking status, alcohol-use status and HIV status
  3. bModel was further adjusted for HPV status