Fig. 5
Knockdown or overexpression of LOCCS affects tumor growth of colon cancer stem cells in nude mice. a Representative tumor growth in nude mice 63 days after they were injected with 1 × 105 TPSC transfected with the siLOCCS or LOCCS-ox plasmid. b Representative tumors dissected from the tumor-bearing mice 63 days after the mice were injected with 1 × 105 TPSC transfected with the siLOCCS or LOCCS-ox plasmid. c Growth curves of tumors in the nude mice and the body weight of the nude mice throughout the 63-day observation period. CT: control group; OX: LOCCS-ox plasmid-transfected group; SI: siLOCCS plasmid-transfected group