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Table 3 Significant genetic associations with cardiometabolic candidate genes

From: Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors

Common Variants

 

Gene

SNP ID

MAF

p-value

FDR

Model

Dyslipidemia

EIF4B

rs146008363

0.05

0.00018

0.180

DOM

OGFOD3

rs62079523

0.33

0.00032

0.180

DOM

Extreme phenotype

BAD

rs2286615

0.10

0.00034

0.200

DOM

FCRL3

rs2282284

0.03

0.00042

0.200

DOM

Common/Rare variants

 

Gene

Rare (n)

Common (n)

p-value

FDR

Extreme phenotype

BAD

3

1

5.79x10-5

0.087

FCRL3

2

1

3.86x10-5

0.087

EIF4B

1

1

0.00010

0.100

  1. MAF Minor allele frequency, DOM Dominant effect, Rare (n) Number of rare variants analyzed in the gene, Common (n) Number of common variants analyzed in the gene, Extreme phenotype Three and more cardiometabolic risk factor
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BMC Cancer

ISSN: 1471-2407

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