Table 3 Comparison of copy number variations (CNVs) between CAISMOV24 cell line and its primary low-grade serous ovarian carcinoma cells
From: CAISMOV24, a new human low-grade serous ovarian carcinoma cell line
Primary maligant cells | CAISMOV24 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Chromosome | CNV | Type | Size (kbp) | Cytoband interval | Gene Count | Chromosome | CNV | Type | Size (kbp) | Cytoband interval | Gene Count |
1 | 1 | Gain | 221 | 1p36.32(3,331,773–3,552,456)×3 | 6 | 1 | 3 | Gain | 113,168 144,332 317,481 | 1p36.33(2,173,472–2,286,640)×0–1 1p36.33(900,361–1,044,693)×2–3 1p36.32(3,324,208–3,641,689)×0–1 | 3 8 7 |
2 | 1 | Gain | 242, 771 | 2p25.3q37.3(12,770–242,783,384)×28–29 | 1494 | 2 | 1 | cnLOH | 242,76 | 2p25.3q37.3(15,702–242,775,910) hmz | 1494 |
3 | 1 | Gain | 197,79 | 3p26.3q29(61,891–197,851,986)×3 | 1279 | 3 | 2 | Loss Gain | 276 197,79 | 3q12.1(98,596,503–98,872,626)×0–1 3p26.3q29(61,891–197,851,986)×3 | 1 1278 |
5 | 1 | Gain | 180,606 | 5p15.33q35.3(113,576–180,719,789)×3 | 1035 | 5 | 1 | Gain | 180,606 | 5p15.33q35.3(113,576–180,719,789)×3 | 1035 |
6 | 1 | Loss | 127 | 6p25.3(254,282–381,137)×1 | 1 | 6 | 1 | Loss | 127 | 6p25.3(254,253–381,137)×1 | 1 |
7 | 3 | Gain Gain Gain | 7818 66,570 83,982 | 7q11.21q11.23(66,698,378–74,516,616)×3 7p22.3q11.21(43,360–66,613,020)×3 7q11.23q36.3(75,137,713–159,119,707)×3 | 58 418 659 | 7 | 4 | Gain Gain Gain Gain | 1695 3221 72,589 80,786 | 7q11.23(72,692,112–74,386,749)×3 7q11.23q21.11(75,034,632–78,255,196)×3 7p22.3q11.23(43,360–72,632,831)×3 7q21.11q36.3(78,333,779–159,119,707)×3 | 33 39 436 626 |
8 | 4 | Loss Gain Gain Gain | 140 4398 39,089 99,432 | 8p11.22(39,247,097–39,386,952)×2 8p11.22p11.1(39,388,765–43,786,723)×4 8p23.3p11.22(158,048–39,246,760)×4 8q11.1q24.3(46,863,521–146,295,771)×4 | 8 | 4 | Loss Gain Gain Gain | 140 4398 39,089 99,432 | 8p11.22(39,247,097–39,386,952)×1 8p11.22p11.1(39,388,765–43,786,723)×4 8p23.3p11.22(158,048–39,246,760)×4 8q11.1q24.3(46,863,521–146,295,771)×4 | 2 33 292 511 | |
9 | 1 | Loss | 209 | 9p21.3(21,887,365–22,096,124)×1 | 4 | 9 | 3 | Gain Gain Gain | 679 3244 21,879 | 9q34.3(139,282,807–139,961,930)×3 9p21.3(22,086,839–25,330,810)×291–292 9p24.3p21.3(203,861–22,082,884)×2–3 | 45 5 102 |
11 | 1 | Gain | 364 | 11p15.5(241,986–606,294)×3 | 21 | ||||||
12 | 4 | Gain Gain Gain Gain | 9834 11,031 28,314 84,394 | 12q12q13.12(39,535,139–49,369,195)×29–30 12p13.33p13.2(173,786–11,204,306)×39–40 12p13.2q12(11,207,579–39,521,153)×39–40 12q13.12q24.33(49,385,726–133,777,902)×39–40 | 68 192 149 778 | 12 | 3 | Loss Gain Gain | 9499 11,276 23,369 | 12q12q13.11(39,441,095–48,940,506)×1 12p13.33p13.2(173,786–11,450,109)×39–40 12p13.2p11.1(11,466,434–34,835,837)×39–40 | 51 198 139 |
13 | 1 | Gain | 95,671 | 13q11q34(19,436,286–115,107,733)×3 | 459 | 13 | 1 | Gain | 95,671 | 13q11q34(19,436,286–115,107,733)×3 | 459 |
14 | 1 | Gain | 86,774 | 14q11.2q32.33(20,511,672–107,285,437)×2–3 | 770 | 14 | 2 | Gain Gain | 13,876 71,619 | 14q32.12q32.33(93,408,967–107,285,437)×29–30 14q11.2q32.12(20,511,672–92,130,966)×29–30 | 238 521 |
16 | 1 | cnLOH | 90,074 | 16p13.3q24.3(89,560–90,163,275) hmz | 955 | 16 | 5 | Loss Gain Gain Loss cnLOH | 124 143 236 291 82,965 | 16p13.3(7,094,531–7,218,941)×1 16p13.3(1,986,979–2,129,528)×3 16p13.3(1,052,879–1,288,518)×3 16p13.3(7,441,425–7,732,737)×1 16p13.3q24.3(7,198,476–90,163,275) hmz | 1 18 6 1 734 |
19 | 1 | Gain | 1142 | 19p13.3(260,911–1,403,381)×24–25 | 51 | 19 | 1 | Gain | 1256 | 19p13.3(260,911–1,517,292)×24–25 | 58 |
20 | 3 | Gain Gain Gain | 1499 5355 55,959 | 20p13(61,568–1,560,550)×3 20q13.32q13.33(57,560,776–62,915,555)×3 20q13.32q13.33(57,560,776–62,915,555)×3 | 34 106 515 | 20 | 3 | Gain Gain Gain | 557 14,149 47,64 | 20p12.1(14,319,185–14,875,738)×3 20p13p12.1(61,568–14,210,343)×3 20p12.1q13.33(15,275,354–62,915,555)×3 | 2 134 518 |
22 | 1 | Gain | 512 | 22q11.22(22,943,460–23,455,803)×25–26 | 6 | 22 | 1 | Gain | 458 | 22q11.22(22,997,802–23,455,803)×24–25 | 4 |
X | 3 | Gain Gain Gain | 182 201 384 | Xq21.31(88,604,293–88,786,664)×3 Xp22.33(2,956,273–3,156,774)×3 Xq21.2(85,297,084–85,680,929)×3 | 0 1 2 | X | 1 | Gain | 74,778 | Xp22.33q13.3(168,546–74,946,70n)×2–3 | 494 |