Fig. 2
From: Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma
Differentially expressed mRNAs in eBL compared to GC B cells. a Heatmap of differentially expressed (DE) miRNAs between eBL tumor cells and GC (Germinal center) B cells. The heatmap shows the hierarchical clustering based on the expression profiles of the 211 DE genes with at least 2-fold difference in expression compared to their normal counterpart. b Volcano plot representing the significance genes (−log of the adjusted p-value) vs the fold change difference in eBL compared to GC B-cells. The red and blue colored circles represent genes which are DE with p < 0.01 and FDR < 0.01. The 132 down-regulated genes in eBL are colored blue (have a negative fold-change value) while the 79 up-regulated genes in eBL are colored red (positive fold-change value)