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Table 4 Comparison of doses to active whole pelvic and lumbar-sacral bone marrow (defined with 18FDG-PET) among the 4 plans

From: Incorporating 18FDG-PET-defined pelvic active bone marrow in the automatic treatment planning process of anal cancer patients undergoing chemo-radiation

  

Plan A

Plan B

Plan C

Plan D

p ≤ 0.05 ANOVA

Fisher-Hayter test

Structure

Parameter

Mean

SD(+/−)

Mean

SD(+/−)

Mean

SD(+/−)

Mean

SD(+/−)

  

ACTPBM

D max

52.67

2.72

52.93

2.82

53.03

2.79

53.18

2.63

NS

 

D mean

29.33

2.38

26.99

2.38

25.76

2.74

26.02

2.69

0.014

A vs C and D

V 5

94.59

4.23

92.85

5.05

92.57

5.32

92.71

5.11

NS

 

V 10

87.84

6.04

85.10

7.10

84.05

7.73

84.35

7.53

NS

 

V 15

82.82

7.06

78.54

7.52

75.17

9.14

75.82

8.44

NS

 

V 20

74.26

7.13

68.58

6.94

63.50

8.59

64.24

8.43

0.015

A vs C and D

V 25

63.49

7.48

56.35

6.90

51.49

7.52

52.18

7.97

0.030

A vs C and D

V 30

52.63

7.17

44.87

6.71

40.27

7.12

41.31

7.71

0.020

A vs C and D

V 35

41.72

6.78

33.35

6.13

30.06

6.43

31.14

6.73

0.010

A vs B,C and D

V 40

28.82

5.67

21.54

5.10

19.94

7.27

20.67

5.24

0.020

A vs B,C and D

V 45

9.16

3.51

7.64

2.75

7.20

2.83

6.91

2.21

NS

 

ACTLSBM

D max

48.46

2.01

48.66

1.51

49.08

1.70

49.13

1.54

NS

 

D mean

37.86

18.56

27.87

4.38

27.35

4.65

27.65

4.40

NS

 

V 5

89.89

8.72

87.71

9.16

87.24

9.48

87.43

9.30

NS

 

V 10

83.87

8.66

79.88

9.49

79.18

10.58

79.32

10.03

NS

 

V 15

79.94

9.09

74.87

9.99

74.19

11.68

74.46

10.64

NS

 

V 20

77.23

9.44

68.80

11.31

67.97

13.53

68.45

11.75

NS

 

V 25

73.13

10.15

60.88

12.60

59.46

14.15

60.71

12.54

NS

 

V 30

66.53

11.19

52.06

13.20

50.07

13.19

51.46

12.97

0.020

A vs B,C and D

V 35

56.95

12.73

42.15

12.79

40.19

11.90

41.42

12.30

0.010

A vs B,C and D

V 40

41.04

14.37

29.81

10.52

28.17

9.40

29.29

9.72

0.050

A vs C

V 45

16.11

12.75

10.53

5.13

9.48

3.92

9.23

3.74

NS

 
  1. Legend: D max maximal dose, D mean mean dose, SD standard deviation, V 5,10,15,20,25,30,35,40,45 relative volume receiving 5,10,15,20,25,30,35,40,45 Gy, PBM pelvic bone marrow, LSBM lumbar-sacral bone marrow, ACT active, A, B, C, D plan A,B,C, D, NS non significant