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Table 6 Summary of previous studies of skip metastasis in PTC (0.6–37.5%)

From: Skip metastasis in papillary thyroid carcinoma is difficult to predict in clinical practice

Authors Year LLNM Positive Skip Positive Skip rate(%) Initial Operation Predictive Factors Reference
Ducci, Appetecchia et al. 1997 ND ND 11.1 ND ND [11]
Coatesworth and MacLennan 2002 ND ND 37.5 ND ND [12]
Koo, Lim et al. 2010 70 12 17.1 Not for All NA [13]
Machens, Holzhausen et al. 2004 66 13 19.7 Not for All Fewer Positive Lymph Nodes [8]
Lee, Wang et al. 2007 46 3 6.5 Yes NA [14]
Roh, Park et al. 2007 22 3 13.6 Recurrence NA [6]
Roh, Kim et al. 2008 52 5 9.6 Yes NA [15]
Wada, Masudo et al. 2008 151 17 11.3 Yes NA [16]
Chung, Kim et al. 2009 12 3 25 Yes NA [17]
Xiao and Gao 2010 64 9 14.1 Yes NA [18]
Kim 2012 490 3 0.6 Yes NA [19]
Kliseska and Makovac 2012 42 8 19.5 ND ND [20]
Lim and Koo 2012 90 17 19 Yes Lymphovascular Invasion, Extracapsular SpreadAnd fewer Positive Lymph Nodes [21]
Park, Lee et al. 2012 147 32 21.8 Yes Single Focus; Locatedupper; Microcarcinoma [22]
Lee, Shin et al. 2014 131 9 6.8 Yes Located upper [23]
Xiang, Xie et al. 2015 44 11 25 Yes NA [24]
  1. NA None analysis; ND No data