Fig. 1
From: PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-017-3694-6/MediaObjects/12885_2017_3694_Fig1_HTML.gif)
Examples of immunoexpression patterns of PTTG1IP and securin in breast carcinomas. PTTG1IP was observed as a diffuse cytoplasmic staining, and scored based on the extent of positive cancer cells as negative (score 0) and mild to strong positivity (scores 1+ − 3+). Securin was observed both in the nucleus and cytoplasm of the cancer cells and classified according to the fraction of positively-staining cancer cells (<10% vs. ≥10% of cancer cells). Examples of nuclear and cytoplasmic staining patterns are indicated with arrows. (200× magnification)