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Fig. 1 | BMC Cancer

Fig. 1

From: Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer

Fig. 1

Schematic representation of the transcript variants and isoforms of ESR2 gene evaluated in this study. a Three primer pairs were used to amplify the ESR2 variants. Primer pair 1, in bold, amplifies five ESR2 transcript variants (a, b, d, f, k and l), representing the isoforms ERβ1, ERβ2 and ERβ4. Primer pair 2, highlighted in dark grey, amplifies the transcript variants a and g (ERβ1 and ERβ5). Primer pair 3, highlighted in light grey, amplifies the variants b, l and k (ERβ2). b The ESR2 transcript variants are indicated by letters, followed by the correspondent isoforms. Figure modified from UCSC Genome Browser (https://genome.ucsc.edu). The nomenclature was defined according to NCBI (https://www.ncbi.nlm.nih.gov/nuccore)

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