Skip to main content

Table 2 The association between birth weight and the risk of CNS tumors

From: The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database

Birth weight Controls CNS tumors OR 95%CI P value
Lower Upper
Total subjects
  < 2500 g 24 7 1.8 0.5 5.8 0.363
 2500- < 3000 g 137 7 0.6 0.2 1.4 0.214
 3000- < 3500 g 305 21 1 Reference  
 3500–4000 g 276 25 1.5 0.8 2.8 0.205
  > 4000 g 80 12 2.9 1.3 6.6 0.012
    P for homogeneity = 0.017
For all: P for trend = 0.010 (beta = 0.0007)
For birth weight ≥ 2500 g:P for trend < 0.001 (beta = 0.0011)
For birth weight 2500–4000 g: P for trend = 0.012 (beta = 0.0011)
  < 2500 g 24 7 2.0 0.7 5.9 0.241
 2500–4000 g 718 53 1 Reference  
  > 4000 g 80 12 2.5 1.2 5.2 0.018
    P for homogeneity = 0.028
The risk of high-birth-weight and LGA children compared to normal-birth-weight childrena
 2500–4000 g 718 53 1 Reference   
  > 4000 g and LGA 48 8 2.7 1.1 6.2 0.035
The risk of high-birth-weight and SGA/AGA children compared to normal-birth-weight childrena
 2500–4000 g 718 53 1 Reference   
  > 4000 g and SGA/AGA 32 4 2.2 0.7 6.7 0.209
  1. LGA large for gestational age, SGA small for gestational age, AGA appropriate for gestational age
  2. ORs and corresponding 95%CIs and p values were adjusted for sex, ethnicity, year of birth, age at diagnosis, gestational age (continuous variable), maternal age and DOE sites
  3. a Children with low-birth weight were not included in the analyses