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Table 3 50% inhibitory concentration of compound 1–3 against various cell lines. The compound 3 showed potent anti-cancer activity against NSCLC cells as compared to cisplatin (standard drug)

From: Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway

  NCI-H460 MCF-7 HeLa NIH-3 T3
Compound 1 0.23 mM ± 0.85 Inactive Inactive 0.42 mM ± 0.13
Compound 2 0.13 mM ± 0.38 Inactive Inactive 0.28 mM ± 0.5
Compound 3 17.86 μM ± 0.72 11.86 μM ± 0.46 32.13 μM ± 0.6 30.32 μM ± 0.93
Cisplatin 19 μM ± 1.24 09.62 μM ± 0.5 16.19 μM ± 0.7