Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-017-3667-9/MediaObjects/12885_2017_3667_Fig5_HTML.gif)
a Gene expression analysis of pro-apoptotic (BAK and BAX) and anti-apoptotic genes (BCL-2 L1 and p53) after 48 h treatment of NCI-H460 cells with compound 3. GAPDH was used as a control housekeeping gene. b Quantitative analysis of the expression by calculating fold change in integrated density treated versus control genes. *** p < 0.001 and ** p < 0.01 when compared to the control