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Table 3 Diagnostic values of miRNAs in conjunction with HPV E6/E7 for cervical cancer

From: MiR-9, miR-21, and miR-155 as potential biomarkers for HPV positive and negative cervical cancer

 

AUCa

95% CI

P-value

All cases

 HPV E6/E7

0.8558

0.7773–0.9343

<0.0001

 HPV E6/E7 + miR-9

0.8135

0.7257–0.9013

<0.0001

 HPV E6/E7 + miR-21

0.8215

0.7349–0.9082

<0.0001

 HPV E6/E7 + miR-155

0.8935

0.8243–0.9626

<0.0001

HPV negative cases

 HPV E6/E7

0.5000

0.3321–0.6679

1.00

 HPV E6/E7 + miR-9

0.6000

0.4284–0.7716

0.24

 HPV E6/E7 + miR-21

0.7267

0.5776–0.8757

0.01

 HPV E6/E7 + miR-155

0.7000

0.5152–0.8648

0.04

  1. a AUC an area under the ROC curve
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BMC Cancer

ISSN: 1471-2407

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