Fig. 5

Tumor development modifies the metabolic profile of the host. (a) Accumulative gain weight along the 13 days after tumor cells inoculation (b) Food ingestion before, on day 7 and day 13 after tumor cells inoculation. Data are the mean ± SEM (n = 7/group). For A and B, the repeated-measures two-way ANOVA indicated a significant effect of time, p < 0.0001. Bonferroni test indicated *p < 0.01 statistical difference from LD, & between LD and # between LL. (c) TG and (d) glucose levels under ad libitum and fasted conditions in LD and LL tumor-bearing rats (13 days) D. Unpaired t test **p > 0.001 indicated statistical difference from LD. Data are the mean ± SEM (n = 7/group). (e) Glucose tolerance test (0–120 min) and (F) AUC following i.p. administration of 1 g glucose/kg. Data are the mean ± SEM (n = 8/group)