Skip to main content

Table 2 Multivariable disease specific survival analysis for PD-L1 expression quantified by percent positive & H-score

From: Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma

Variable Comparison Risk ratio 95%CI p-value
PD-L1 H-Score
PD-L1 H-Score Per unit change 1.01 0.997–1.02 0.10
Age at Surgery Per unit change 1.01 0.991–1.02 0.44
Sex Male v Female 1.14 0.85–1.53 0.37
Adjuvant Chemotherapy Given v Observation 0.59 0.42–0.81 0.0011
Histopathologic Grade 1 v 2 0.63 0.10–2.10 0.50
1 v 3 0.49 0.08–1.67 0.28
2 v 3 0.77 0.55–1.09 0.13
Lymphovascular Invasion Present v Absent 1.27 0.93–1.74 0.13
Perineural Invasion Present v Absent 1.66 0.96–3.09 0.07
pN-Stage 1 v 0 1.83 1.27–2.68 0.0010
Resection Status R0 v R1 0.67 0.49–0.94 0.0202
PD-L1 Percent Positive
PD-L1 Percent Positive Per unit change 1.03 1.0005–1.05 0.0466
Age at Surgery Per unit change 1.0006 0.99–1.02 0.42
Sex Male v Female 1.16 0.86–1.55 0.33
Adjuvant Chemotherapy Given v Observation 0.58 0.42–0.80 0.0008
Histopathologic Grade 1 v 2 0.64 0.10–2.13 0.51
1 v 3 0.50 0.08–1.71 0.30
2 v 3 0.78 0.56–1.10 0.15
Lymphovascular Invasion Present v Absent 1.28 0.94–1.76 0.12
Perineural Invasion Present v Absent 1.68 0.98–3.13 0.06
pN-Stage 1 v 0 1.85 1.28–2.71 0.0009
Rescetion Status R0 v R1 0.68 0.49–0.95 0.0189