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Table 1 Correlation between FOXP3 expressin in tumor cells and clinicopathologic characteristics (n = 240)

From: FOXP3 Is a HCC suppressor gene and Acts through regulating the TGF-β/Smad2/3 signaling pathway

Variables FOXP3 staining P
  Low (n = 125) High (n = 115)  
  n (%) n (%)  
Age (years)
  ≤ 50 59 (47.2) 53 (46.1) 0.897
  > 50 66 (52.8) 62 (53.9)  
Gender
 Male 103 (82.4) 101 (87.8) 0.280
 Female 22 (17.6) 14 (12.2)  
HBsAg
 Negative 10 (8.0) 7 (6.1) 0.622
 Positive 115 (92.0) 108 (93.9)  
Liver cirrhosis
 No 12 (9.6) 16 (13.9) 0.321
 Yes 113 (90.4) 99 (86.1)  
Serum AFP (ng/mL)
  ≤ 20 34 (27.2) 48 (41.7) 0.021
  > 20 91 (72.8) 67 (58.3)  
Tumor size (cm)
  ≤ 5 57 (45.6) 60 (52.2) 0.366
  > 5 68 (54.4) 55 (47.8)  
Tumor number
 Single 98 (78.4) 86 (74.8) 0.543
 Multiple 27 (21.6) 29 (25.2)  
Tumor encapsulation
 Yes 58 (46.4) 61 (53.0) 0.366
 No 67 (53.6) 54 (47.0)  
Vascular invasion
 No 53 (42.4) 72 (62.6) 0.002
 Yes 72 (57.6) 43 (37.4)  
Tumor differentiation
 I/II 71 (56.8) 64 (55.7) 0.897
 III/IV 54 (43.2) 51 (44.3)  
BCLC
 0/A 54 (43.2) 60 (52.2) 0.196
 B/C 71 (56.8) 55 (47.8)  
TNM stage
 I 46 (36.8) 60 (52.2) 0.019
 II/III 79 (63.2) 55 (47.8)