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Table 3 Multivariable Cox regression analysis of recurrence-free survival

From: Adjuvant chemotherapy versus chemoradiotherapy for small cell lung cancer with lymph node metastasis: a retrospective observational study with use of a national database in Japan

  Hazard ratio 95% Confidence interval P
Adjuvant therapy
 Chemotherapy Reference   
 Chemoradiotherapy 1.29 0.91–1.84 0.15
N factor
 N1 Reference   
 N2 1.22 0.94–1.59 0.14
T factor
 T0-1 Reference   
 T2 1.11 0.82–1.50 0.50
 T3-4 1.09 0.77–1.56 0.63
Age (years)
 18–49 Reference   
 50–64 1.27 0.62–2.59 0.51
 65–74 1.27 0.64–2.55 0.50
  ≥ 75 1.46 0.69–3.09 0.33
Sex
 Male Reference   
 Female 0.77 0.54–1.10 0.15
Body mass index(kg/m2)
  < 18.5 1.42 0.87–2.31 0.16
 18.5–24.9 Reference   
  ≥ 25 1.30 0.96–1.75 0.09
Charlson comorbidity index
 0–2 Reference   
  ≥ 3 1.81 1.39–2.35 <0.001
Activity of daily life (Barthel index)
 Independent (100–95) Reference   
 Dependent (≤90) 1.80 0.87–3.75 0.12