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Table 4 Correlation between clinicopathological features and β-tubulin class III, GSTP1, and TLE3 expression in 22 triple-negative breast cancers

From: Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer

Parameters

 

β-tubulin class III

p value

GSTP1

p value

TLE3

p value

Positive (n = 7)

Negative (n = 15)

Positive (n = 13)

Negative (n = 9)

Positive (n = 14)

Negative (n = 8)

Age at operation

 ≤63

4 (57.1%)

8 (53.3%)

0.616

6 (46.2%)

6 (66.7%)

0.305

9 (64.3%)

3 (37.5%)

0.221

 >63

3 (42.9%)

7 (46.7%)

7 (53.8%)

3 (33.3%)

5 (35.7%)

5 (62.5%)

Degree of progress

 Locally advanced

0 (0.0%)

6 (40.0%)

0.067

3 (23.1%)

3 (33.3%)

0.477

2 (14.3%)

4 (50.0%)

0.096

 Visceral metastases

7 (100.0%)

9 (60.0%)

10 (76.9%)

6 (66.7%)

12 (85.7%)

4 (50.0%)

Life threatening condition

 non- Life threatening

4 (57.1%)

5 (33.3%)

0.276

5 (38.5%)

4 (44.4%)

0.561

8 (57.1%)

1 (12.5%)

0.052

 Life threatening

3 (42.9%)

10 (66.7%)

8 (61.5%)

5 (55.6%)

6 (42.9%)

7 (87.5%)

Nuclear grade

 1, 2

1 (14.3%)

4 (26.7%)

0.477

4 (30.8%)

1 (11.1%)

0.293

4 (28.6%)

1 (12.5%)

0.380

 3

6 (85.7%)

11 (73.3%)

9 (69.2%)

8 (88.9%)

10 (71.4%)

7 (87.5%)

Ki67

 Negative

3 (42.9%)

8 (53.3%)

0.500

7 (53.8%)

4 (44.4%)

0.500

8 (57.1%)

3 (37.5%)

0.330

 Positive

4 (57.1%)

7 (46.7%)

6 (46.2%)

5 (55.6%)

6 (42.9%)

5 (62.5%)

  1. GSTP 1 glutathione S-transferase pi 1, TLE3 transducin-like enhancer of split 3, HER2 human epidermal growth factor receptor 2, TNBC triple-negative breast cancer