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Table 5 Reasons for not receiving GDT (n = 106)

From: Comprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy

Reason

Frequency (%)

No actionable mutations

11 (10%)

Disease in remission/no indication for therapy

18 (17%)

Patient still receiving standard of care/off-label option or clinical trial not suggested by F1 report

42 (40%)

Patient is no longer a candidate for therapy due to deteriorating or poor performance status

25 (23%)

Physician preference for no GDT specifically because of rapid disease

5 (5%)

On/off label GDT recommended or clinical trial available locally but patient declined

3 (3%)

Patient offered clinical trial but unable to travel/insurance decline

2 (2%)