LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

BMC Cancer

Table 3 Association between hrHPV status and LINE-1 methylation levels (logistic regression analysis adjusting for age, BMI, smoking status and parity)

	β (SE)	p-value ^a	adjOR	95% CI
	β (SE)	p-value ^a	adjOR	Lower	Upper
LINE-1 methylation level (continuous)	0.011 (0.047)	0.809	1.01	0.92	1.11
Age (continuous)	−0.014 (0.28)	0.633	0.97	0.93	1.04
BMI (continuous)	−0.076 (0.062)	0.220	0.93	0.82	1.05
Smoking status (current)	0.997 (0.493)	0.043	2.71	1.03	7.12
Parity (<1 live births)	1.302 (0.629)	0.038	3.68	1.07	12.61

Abbreviations: SE standard error, adjOR adjusted Odds Ratio, CI Confidence Interval, LINE-1 Long Interspersed Nuclear Element- 1
^aStatistically significant p values (p < 0.05) are indicated in bold font

ISSN: 1471-2407