Table 6 Failure analysis in P67.5 and P70 study
Failure patterns | Num of patients | Median failure time month (range) | Num of salvage treatment (%) | Num of death (%) | Median time from failure to death month (range) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
P67.5 | P70 | P67.5 | P70 | P67.5 | P70 | P67.5 | P70 | P67.5 | P70 | |
Local recurrence | 5 | 6 | 22.0 (15–29) | 12.8 (5–34) | 3 (60%) | 2 (33%) | 3 (60%) | 4 (67%) | 10.3 (3–18) | 4.0 (1–7) |
 In-field | 3 | 4 | 24.3 (21–29) | 15.0 (6–34) | 2 (66%) | 1 (25%) | 2 (66%) | 3 (75%) | 6.5 (3–10) | 3.6 (1–7) |
 Marginal | 2 | 2 | 18.5 (15–22) | 8.5 (5–12) | 1 (50%) | 1 (50%) | 1 (50%) | 1 (50%) | 18 | 5 |
Reginal recurrence | 3 | 3 | 25.6 (23–30) | 16.7 (10–24) | 3 (100%) | 3 (100%) | 0 | 2 (67%) | - | 12.5 (12–13) |
Distant metastasis | 10 | 11 | 10.9 (4–26) | 19.4 (3–38) | 5 (50%) | 5 (45%) | 9 (90%) | 9 (82%) | 8.3 (3–19) | 8.5 (0–35) |
 Liver | 5 | 3 | 14.8 (12–16) | 20.3 (3–29) | 2 (40%) | 0 | 4 (80%) | 3 (100%) | 7.5 (3–19) | 3.7 (1–5) |
 Bone | 3 | 4 | 6.3 (4–9) | 17.5 (3–38) | 2 (67%) | 2 (50%) | 3 (100%) | 3 (75%) | 9.0 (3–13) | 13.7 (0–35) |
 Lung | 1 | 0 | 8 | - | 1 (100%) | - | 1 (100%) | - | 13 | - |
 Multiple or others | 1 | 4 | 8 | 20.5 (10–30) | 0 | 3 (75%) | 1 (100%) | 3 (75%) | 5 | 8.3 (1–17) |
Hemorrhage | 1 | 5 | 10 | 9.2 (6–12) | 0 | 0 | 1 (100%) | 5 (100%) | 0 | 0 |
Other patterns | 0 | 1 | - | 12 | - | 0 | - | 1 (100%) | - | 0 |