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Table 6 Failure analysis in P67.5 and P70 study

From: Propensity score matching analysis of a phase II study on simultaneous modulated accelerated radiation therapy using helical tomotherapy for nasopharyngeal carcinomas

Failure patterns Num of patients Median failure time month (range) Num of salvage treatment (%) Num of death (%) Median time from failure to death month (range)
P67.5 P70 P67.5 P70 P67.5 P70 P67.5 P70 P67.5 P70
Local recurrence 5 6 22.0 (15–29) 12.8 (5–34) 3 (60%) 2 (33%) 3 (60%) 4 (67%) 10.3 (3–18) 4.0 (1–7)
 In-field 3 4 24.3 (21–29) 15.0 (6–34) 2 (66%) 1 (25%) 2 (66%) 3 (75%) 6.5 (3–10) 3.6 (1–7)
 Marginal 2 2 18.5 (15–22) 8.5 (5–12) 1 (50%) 1 (50%) 1 (50%) 1 (50%) 18 5
Reginal recurrence 3 3 25.6 (23–30) 16.7 (10–24) 3 (100%) 3 (100%) 0 2 (67%) - 12.5 (12–13)
Distant metastasis 10 11 10.9 (4–26) 19.4 (3–38) 5 (50%) 5 (45%) 9 (90%) 9 (82%) 8.3 (3–19) 8.5 (0–35)
 Liver 5 3 14.8 (12–16) 20.3 (3–29) 2 (40%) 0 4 (80%) 3 (100%) 7.5 (3–19) 3.7 (1–5)
 Bone 3 4 6.3 (4–9) 17.5 (3–38) 2 (67%) 2 (50%) 3 (100%) 3 (75%) 9.0 (3–13) 13.7 (0–35)
 Lung 1 0 8 - 1 (100%) - 1 (100%) - 13 -
 Multiple or others 1 4 8 20.5 (10–30) 0 3 (75%) 1 (100%) 3 (75%) 5 8.3 (1–17)
Hemorrhage 1 5 10 9.2 (6–12) 0 0 1 (100%) 5 (100%) 0 0
Other patterns 0 1 - 12 - 0 - 1 (100%) - 0