Table 2 Survival groups by favourable biomarker status
Factor | Short survival | Long survival | Unadjusted | Adjustedc | ||
|---|---|---|---|---|---|---|
ORa (95% CI) | P b | ORa (95% CI) | P | |||
BRAF | ||||||
 Wildtype | 10 (43) | 13 (57) | 2.8 (0.8-10) | 0.11 | 4.5 (0.7-27) | 0.10 |
 Mutation | 13 (68) | 6 (32) | 1 |  | 1 |  |
Ki67 | ||||||
 Low | 9 (38) | 15 (63) | 5.8 (1.5-23) | 0.013 | 26.1(2.0-344) | 0.013 |
 High | 14 (78) | 4 (22) | 1 |  | 1 |  |
FOXP3 | ||||||
 Low | 13 (65) | 7 (35) | 1 | 0.21 | 1 | 0.42 |
 High | 10 (45) | 12 (55) | 2.2 (0.6-7.7) |  | 1.9 (0.4-9.4) |  |
CD8 | ||||||
 Low | 15 (68) | 7 (32) | 1 | 0.071 | 1 | 0.17 |
 High | 8 (40) | 12 (60) | 3.2 (0.9-11) |  | 3.0 (0.6-15) |  |
Number of favourable markers out of the above 4 | ||||||
 At least 3 | 4 (25) | 12 (75) | 8.1 (2.0-34) | 0.004 | 19.4 (1.9-197) | 0.012 |
 Less than 3 | 19 (73) | 7 (27) | 1 |  | 1 |  |