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Table 2 Clinical characteristics of patients with FOLFOX therapy related pulmonary disease treated with discontinuation of chemotherapy

From: Prognosis and treatment of FOLFOX therapy related interstitial pneumonia: a plea for multimodal immune modulating therapy in the respiratory insufficient patient

Reference

Patient Gender/Age

Preexisting lung disease with the exception of lung metastasis

Smoking

Symptomes

0xygen supplement

Pulmonary function tests

Gagnadoux

F/60

None

No

Cough, progressive dyspnea on exertion

None

FEV1 1.980 L (90%) TLC 4.207 L (90%)

DLCO 4.4 ml/mmHg/min (59%)

Ruiz Casado

M/67

CT: some signs of pulmonary fibrosis in the basal portions

NA

None

None

NA

Wilcox

F/77

None

No

Dry cough, dyspnea on exertion

None

Normal lung volumes

DLCO 9.3 ml/mmHg/min (54%)

Park

M/76

Bronchial asthma

Ex-smoker 40 pack years

General systemic weakness, loss of appetite

None

FVC 2.26 L (95%)

FEV 1 1.46 L (92%)

DLCO 10,8 ml/min/mmHg (109%)

Basyigit

M/60

None

Ex-smoker 14 pack years

Dyspnea on exertion

None

NA

  1. FEV1 Forced Expiratory Volume In One Second, FVC Forced Vital Capacity, TLC Total Lung Capacity, DL CO Diffusing Capacity of carbon monoxide, NA Not Available