Fig. 2

lung tissue (day 14, open-lung biopsy, staining Hematoxylin Eosin) exhibiting a pattern compatible with on-going damage of the alveolar epithelium with evolving pulmonary fibrosis. a magnification 37×: histology (wedge biopsy) revealing lung tissue with a disturbed architecture. The alveolar septa are thickened in a non-specific interstitial pneumonia (NSIP) pattern with lymphocytic inflammatory infiltrate and fibrosis. b magnification 185×: the alveolar lumina exhibit the presence of an exudate. c Magnification 380×: reactive cuboid pneumocytes line the alveolar lumina. This picture is consistent with interstitial pneumonitis