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Table 3 Multivariate Analyses

From: Chemoradiotherapy versus surgery followed by postoperative radiotherapy in tonsil cancer: Korean Radiation Oncology Group (KROG) study

 

OS

DFS

LRRFS

DMFS

Characteristics

p-value

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

Age (years)

 ≥ 60

<0.001

3.000

2.001–4.497

<0.001

2.516

1.779–3.560

   

0.009

2.227

1.217–4.077

Smoking history

 Current smoker

0.012

1.663

1.116–2.478

0.015

1.54

1.089–2.176

0.014

1.919

1.141–3.226

   

Performance status

 ECOG 1–2

0.045

1.566

1.010–2.426

0.017

1.587

1.087–2.315

0.019

2.094

1.130–3.879

   

T stage

 T3–T4

<0.001

2.913

1.943–4.366

<0.001

2.572

1.808–3.659

0.021

1.852

1.097–3.127

<0.001

3.312

1.804–6.082

N stage

 N2c–N3

0.069

1.542

0.966–2.462

0.008

1.735

1.155–2.607

0.075

1.747

0.946–3.226

0.007

2.435

1.271–4.664

Chemotherapy

 Induction

0.003

2.224

1.313–3.768

0.033

1.712

1.044–2.806

      
  1. Abbreviations: OS overall survival, DFS disease-free survival, LRRFS locoregional recurrence-free survival, DMFS distant metastasis-free survival, HR hazard ratio, CI confidence interval, ECOG Eastern Cooperative Oncology Group
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BMC Cancer

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