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Table 4 Association between Adherence and Any, Breast, Colorectal and Prostate Cancer Incidence by Race, NIH-AARP Diet and Health Study

From: Cancer-related risk factors and incidence of major cancers by race, gender and region; analysis of the NIH-AARP diet and health study

Any Cancer HR (95% CI)

Breast Cancer HR (95% CI)

Prostate Cancer HR (95% CI)

Colorectal Cancer HR (95% CI)

 

All

White

AA

All

White

AA

All

White

AA

All

White

AA

Obesity

 0

1.08 (1.06 -1.1)

1.08 (1.06 - 1.1)

0.91 (0.83 - 0.99)

1.16 (1.1 - 1.22)

1.14 (1.09 - 1.2)

1.1 (0.89 - 1.37)

0.87 (0.84-0.89)

0.87 (0.84 -.89)

0.89 (0.76 - 1.03)

1.3 (1.22 - 1.38)

1.29 (1.2-1.37)

1.09 (0.83 - 1.43)

 0.5

1.04 (1.03 -1.05)

1.04 (1.03 -1.05)

0.95 (0.91 - 0.99)

1.08 (1.05 - 1.1)

1.07 (1.04 -1.09)

1.05 (0.94 - 1.17)

0.93 (0.91-0.95)

0.93 (0.92 -0.95)

0.94 (0.87 - 1.02)

1.14 (1.11 -1.17)

1.14 (1.11 -1.17)

1.04 (0.91 - 1.2)

  P-trend

<0.001

<0.001

0.031

<0.001

<0.001

0.3713

<0.001

<0.001

0.1258

<0.001

<0.001

0.53

Alcohol

 0

1.55 (1.43 -1.68)

1.54 (1.44 -1.66)

1.64 (1.16 - 2.31)

1.78 (1.26 - 2.51)

1.5 (1.07 - 2.09)

2.71 (1.06 - 6.9)

1.08 (0.92 -1.27)

1.04 (0.89 - 1.2)

1.05 (0.56 - 1.95)

2.02 (1.59 -2.58)

1.99 (1.59 -2.47)

3.64 (1.6 - 8.27)

 0.5

1.24 (1.19 -1.29)

1.24 (1.2 -1.29)

1.28 (1.08 - 1.52)

1.33 (1.12 - 1.59)

1.22 (1.04 -1.45)

1.64 (1.03 - 2.63)

1.04 (0.96 -1.13)

1.02 (0.94 - 1.1)

1.02 (0.75 - 1.4)

1.42 (1.26 -1.61)

1.41 (1.26 -1.57)

1.91 (1.27 - 2.88)

  P-trend

<0.001

<0.001

<0.001

<0.001

0.01763

0.037

0.359

0.65

0.89

<0.001

<0.001

0.0036

Smoking

 0

1.68 (1.65 -1.72)

1.7 (1.67 - 1.74)

1.63 (1.49 - 1.79)

1.11 (1.05 - 1.18)

1.12 (1.06 -1.18)

1.28 (1.02 - 1.6)

0.83 (0.79 -0.86

0.82 (0.79 - .86)

0.88 (0.75 - 1.05)

1.41 (1.32 -1.51)

1.42 (1.33 -1.51)

1.3 (0.97 - 1.73)

 0.5

1.3 (1.28 -1.31)

1.31 (1.29 -1.32)

1.28 (1.22 - 1.34)

1.06 (1.03 - 1.09)

1.06 (1.03 -1.09)

1.13 (1.01 - 1.27)

0.91 (0.89-0.93)

0.91 (0.89 -0.93)

0.94 (0.86 - 1.02)

1.19 (1.15 -1.23)

1.19 (1.15 -1.23)

1.14 (0.99 -1.31)

  P-trend

0

0

<0.001

<0.001

<0.001

0.033

<0.001

<0.001

0.1589

<0.001

<0.001

0.07298

Nutrition

 0

1.11 (1.09 -1.13)

1.11 (1.1 - 1.13)

1.09 (1.01 - 1.17)

1.07 (1.01 - 1.12)

1.07 (1.02 -1.12)

1.13 (0.94 - 1.37)

1.02 (0.99 -1.05)

1.02 (0.99 -1.05)

0.93 (0.82 - 1.06)

1.13 (1.07 -1.19)

1.13 (1.08 - 1.2)

1.15 (0.92 - 1.44)

 0.5

1.05 (1.04 -1.06)

1.05 (1.05 -1.06)

1.04 (1.01 - 1.08)

1.03 (1.01 - 1.06)

1.04 (1.01 -1.06)

1.06 (0.97 - 1.17)

1.01 (0.99 -1.03)

1.01 (0.99 -1.03)

0.96 (0.91 - 1.03)

1.06 (1.03 -1.09)

1.07 (1.04 -1.09)

1.07 (0.95 - 1.2)

  P-trend

<0.001

<0.001

0.025

0.01495

0.004

0.199

0.254

0.174

0.2847

<0.001

<0.001

0.2305

Physical Activity

 0

1.15 (1.13 -1.18)

1.15 (1.13 -1.17)

1.18 (1.07 - 1.3)

1.12 (1.05 - 1.19)

1.11 (1.05 -1.18)

1.28 (0.99 - 1.67)

0.94 (0.90-0.97)

0.92 (0.88 -0.95)

1.04 (0.87 - 1.24)

1.33 (1.24 -1.42)

1.35 (1.26 -1.44)

1.15 (0.85 -1.56)

 0.5

1.07 (1.06 -1.09)

1.07 (1.06 -1.08)

1.09 (1.03 - 1.14)

1.06 (1.03 - 1.09)

1.05 (1.02 -1.09)

1.13 (0.99 - 1.29)

0.97 (0.95-0.99)

0.96 (0.94 -0.98)

1.02 (0.93 - 1.11)

1.15 (1.11 -1.19)

1.16 (1.12 - 1.2)

1.07 (0.92 - 1.25)

  P-trend

<0.001

<0.001

<0.001

<0.001

<0.001

0.063

0.001

<0.001

0.68

<0.001

<0.001

0.3624

Overall Adherence

 1

1.76 (1.7 -1.82)

1.76 (1.7 - 1.82)

1.69 (1.42 - 2)

1.38 (1.26 - 1.52)

1.38 (1.25 -1.52)

1.45 (0.93 - 2.25)

0.79 (0.75-0.85)

0.70 (0.74 -0.84)

0.98 (0.73 - 1.33)

2.06 (1.84 -2.29)

2.07 (1.86 -2.32)

1.64 (0.96 - 2.79)

 2

1.53 (1.49 -1.56)

1.53 (1.49 -1.57)

1.48 (1.3 - 1.68)

1.28 (1.19 - 1.37)

1.27 (1.19 -1.37)

1.32 (0.95 - 1.84)

0.84 (0.80-0.88)

0.84 (0.79 -0.88)

0.98 (0.79 - 1.24)

1.72 (1.58 -1.86)

1.73 (1.59 -1.88)

1.45 (0.97- 2.16)

 3

1.33 (1.3 -1.35)

1.33 (1.31 -1.35)

1.31 (1.19 - 1.42)

1.18 (1.12 - 1.23)

1.18 (1.12 -1.23)

1.2 (0.96 - 1.5)

0.89 (0.86-0.92)

0.89 (0.86 -0.92)

0.99 (0.85 - 1.15)

1.43 (1.36 -1.51)

1.44 (1.36 -1.52)

1.28 (0.98 - 1.67)

 4

1.15 (1.14 -1.16)

1.15 (1.14 -1.16)

1.14 (1.09 - 1.19)

1.08 (1.06 - 1.11)

1.08 (1.06 -1.11)

1.1 (0.98 - 1.23)

0.94 (0.93-0.96)

0.94 (0.93 -0.96)

0.99 (0.92 - 1.07)

1.2 (1.17 - 1.23)

1.2 (1.17 - 1.23)

1.13 (0.99 - 1.29)

  P-trend

<0.001

<0.001

<0.001

<0.001

<0.001

0.101

<0.001

<0.001

0.9207

<0.001

<0.001

0.06741

  1. All models estimated using Cox Proportional Hazards regression and adjusted for age, gender (for colorectal cancer), marital status, and education
  2. Abbreviations: CI confidence interval, AA African-Americans