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Table 3 Characteristics of interval cancers and screen-detected colorectal cancer

From: Population-based colorectal cancer screening programmes using a faecal immunochemical test: should faecal haemoglobin cut-offs differ by age and sex?

Total Interval cancersa Screen-detected p-value
First round Second round
136 (83.3%; 1st round/16.2%; 2nd round) 889 143 -
Sex
 Men; n (%) 89 (65.4) 594 (66.8) 99 (69.2) 0.79
 Women; n (%) 47 (34.6) 295 (33.2) 44 (30.8)
Age (years)
 50–54; n (%) 26 (19.1) 137 (15.4) 19 (13.3) 0.06
 55–59; n (%) 32 (23.5) 195 (21.9) 42 (29.4)
 60–64; n (%) 45 (33.1) 260 (29.2) 43 (30.1)
 65–69; n (%) 33 (24.3) 297 (33.4) 39 (27.3)
μg Hb/g faeces; median (IQR) 2.9 (0.4–11.6)b 201.8 (74.4–589.8)c 638.3 (56.8–617.2)c -
Location (proximal side/distal side/rectum)c; % 34.3 / 33.6 / 32.1 18.1 / 67.0 / 14.9 21.6 / 66.3 / 12.1 <0.001
Stage (I-II/III-IV); % 44.8 / 55.2 66.7 / 28.4 65.7 / 24.6 <0.001
Size (cm); median (IQR) 8 (6.0–12.0) 2.5 (1.5–4.0) 2.5 (1.5–3.5) <0.001
Time to diagnosis     
 Within 1 year; n (%) 64 (47.1)    -
 1–2 years; n (%) 72 (52.9)   
  1. aInterval cancers after a negative test result in the previous round
  2. bMedian μg Hb/g faeces at time of negative screening test result. **Median μ Hb/g faeces at time of positive screening test result
  3. cProximal side includes regions from cecum up to and including the transverse colon; distal side includes splenic flexure, descending colon and sigmoid colon