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Table 3 Summary of the findings regarding the PC, LPC, PE, and LPE detected in this study

From: Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer

  The number of molecules (Tumor/Normal) The number of molecules (EP + H−/Normal) The number of molecules (TN/Normal) The number of molecules (TN/EP + H-)
All Significant higher Significant lower All Significant higher Significant lower All Significant higher Significant lower All Significant higher Significant lower
PC 84 (4) 78 4 84 (1) 72 1 84 (1) 74 0 84 (2) 34 0
LPC 43 (36) 31 2 43 (33) 26 4 43 (15) 24 0 43 (19) 1 0
PE 73 (17) 68 2 73 (13) 69 0 73 (11) 62 0 73 (3) 18 1
LPE 22 (13) 19 0 22 (7) 13 0 22 (11) 12 0 22 (15) 0 1
  1. Table 3 shows comparisons of the levels of the PC, LPC, PE, and LPE detected using LC/MS between the breast cancer tissue samples and the corresponding normal breast tissue samples, between the EP + H- tumors and the corresponding normal breast tissue samples, between the TN tumors and the corresponding normal breast tissue samples, and between the TN tumors and the EP + H- tumors. The numbers in parentheses indicate the numbers of PC, LPC, PE, and LPE that were not detected in the paired samples. Significant higher are indicated as follows: tumor > normal, EP + H- > normal, TN > normal, TN > EP + H-, and significant lower are shown as follows: tumor < normal, EP + H- < normal, TN < normal, TN < EP + H- (p < 0.05 in both cases). The Wilcoxon signed-rank test was used for comparisons of PC, LPC, PE, and LPE levels between the pairs of breast cancer tissue samples and normal breast tissue samples, and the Mann-Whitney U-test was used for comparisons involving the metabolites that were not detected in the paired samples