Outcomes | Instrument | Baseline | 12-week | 24-week |
---|---|---|---|---|
Primary outcome | ||||
 Quality of life | EORTC-QLQ-C30 | X | X | X |
Secondary outcomes | ||||
 Esophageal cancer specific symptoms | EORTC-QLQ-OG25 | X | X | X |
 Fatigue | Multidimensional Fatigue Inventory (MFI) | X | X | X |
 Anxiety and depression | Hospital Anxiety and Depression Scale (HADS) | X | X | X |
 Sleep quality | Pittsburgh Sleep Quality Index (PSQI) | X | X | X |
 Work-related factors | iMTA Productivity Cost Questionnaire (iPCQ) | X | X | X |
 Cardiorespiratory fitness | Cardiopulmonary exercise testing (CPET) | X | X |  |
 Muscle strength | MicroFET handheld dynamometer | X | X |  |
 Physical activity | Short questionnaire to assess health enhancing physical activity (SQUASH) | X | X | X |
 | ActiGraph accelerometer | X | X | X |
 | Exercise log |  | X |  |
 Malnutrition risk | Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF) | X | X | X |
 Dietary intake | 3-Day food diary | X | X | X |
 Anthropometry | Body weight, height, BMI, waist and hip circumference | X | X |  |
 Blood parameters | Serum, plasma and cell pellet | X | X |  |
 Adherence and compliance | Registration in case report form, exercise log | X | X |  |
 Recurrence and survival | Medical records and Dutch Cancer Registry |  |  |  |
Other | ||||
 Sociodemographic data | Self-developed questionnaire | X |  |  |
 Medical data | Medical records | X |  |  |
 Adverse events | Reports of patients, physiotherapists, oncology nurses, physicians, medical records | X | X | X |