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Table 2 Study outcomes

From: Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) study: design of a randomized controlled trial

Outcomes

Instrument

Baseline

12-week

24-week

Primary outcome

 Quality of life

EORTC-QLQ-C30

X

X

X

Secondary outcomes

 Esophageal cancer specific symptoms

EORTC-QLQ-OG25

X

X

X

 Fatigue

Multidimensional Fatigue Inventory (MFI)

X

X

X

 Anxiety and depression

Hospital Anxiety and Depression Scale (HADS)

X

X

X

 Sleep quality

Pittsburgh Sleep Quality Index (PSQI)

X

X

X

 Work-related factors

iMTA Productivity Cost Questionnaire (iPCQ)

X

X

X

 Cardiorespiratory fitness

Cardiopulmonary exercise testing (CPET)

X

X

 

 Muscle strength

MicroFET handheld dynamometer

X

X

 

 Physical activity

Short questionnaire to assess health enhancing physical activity (SQUASH)

X

X

X

 

ActiGraph accelerometer

X

X

X

 

Exercise log

 

X

 

 Malnutrition risk

Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF)

X

X

X

 Dietary intake

3-Day food diary

X

X

X

 Anthropometry

Body weight, height, BMI, waist and hip circumference

X

X

 

 Blood parameters

Serum, plasma and cell pellet

X

X

 

 Adherence and compliance

Registration in case report form, exercise log

X

X

 

 Recurrence and survival

Medical records and Dutch Cancer Registry

   

Other

 Sociodemographic data

Self-developed questionnaire

X

  

 Medical data

Medical records

X

  

 Adverse events

Reports of patients, physiotherapists, oncology nurses, physicians, medical records

X

X

X