Table 4 Univariate and multivariate analysis of factors associated with recurrence in HCC patients (n = 174)
RFS | ||||||
|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||||
HR | 95% CI | P | HR | 95% CI | P | |
Gender (Female vs. Male) | 0.816 | 0.492–1.352 | 0.422 | |||
Age, years (≤ 50 vs. > 50) | 1.342 | 0.922–1.953 | 0.117 | |||
HBsAg (Negative vs. Positive) | 2.518 | 1.225–5.176 | 0.008* | 2.580 | 1.252–5.305 | 0.014* |
Child-Pugh classification (A vs. B) | 1.824 | 0.799–4.165 | 0.154 | |||
Serum AFP, ng/ml (≤ 20 vs. > 20) | 1.103 | 0.738–1.648 | 0.627 | |||
Tumor Number (Single vs. Multiple) | 1.333 | 0.827–2.148 | 0.229 | |||
Tumor size, cm (≤ 5 vs. > 5) | 1.841 | 1.236–2.740 | 0.002* | 1.530 | 1.013–2.306 | 0.043* |
Tumor capsule (No/ incomplete vs. Yes) | 0.78 | 0.535–1.136 | 0.187 | |||
Vascular invasion (N0 vs. Yes) | 1.706 | 0.828–3.515 | 0.136 | |||
Liver cirrhosis (Absent vs. Present) | 1.109 | 0.669–1.839 | 0.682 | |||
Differentiation grade (I / II vs. III/IV) | 1.481 | 1.017–2.158 | 0.036* | 1.224 | 0.823–1.791 | 0.327 |
TNM stage (I vs. II/III) | 1.479 | 0.975–2.244 | 0.06 | |||
KOR (Positive vs. Negative) | 0.626 | 0.516–0.760 | < 0.001* | 0.669 | 0.543–0.810 | < 0.001* |