Table 2 RNA-seq of lung tissue in WT and Angpt1 Δ/Δ mice
From: Angiopoietin-1 deficiency increases tumor metastasis in mice
Gene | Sign. Change | WT | Angpt1KO |
|---|---|---|---|
Angpt1 | ↓ | 22.0 ± 6.2 | 0.5 ± 0.1 |
Angpt2 |  | 16.6 ± 0.5 | 14.4 ± 2.1 |
Angpt4 |  | 0.4 ± 0.09 | 0.5 ± 0.11 |
Angpl1/Angpt3 |  | 1.6 ± 0.15 | 1.7 ± 0.72 |
Angptl2 |  | 35.8 ± 2.7 | 34.0 ± 0.9 |
Angptl3 |  | 0.9 ± 0.4 | 0.8 ± 0.1 |
Angptl4 |  | 8.7 ± 0.4 | 13.9 ± 2.0 |
Angptl6 |  | 1.2 ± 0.4 | 1.8 ± 0.3 |
Angptl7 |  | 1.2 ± 0.3 | 1.5 ± 0.5 |
Tek/Tie2 |  | 144 ± 12 | 130 ± 4 |
Tie1 |  | 57 ± 2 | 57 ± 4 |
Vegfa |  | 437 ± 47 | 509 ± 39 |
Kdr/Vegfr2 |  | 138 ± 8 | 146 ± 2 |
Flt/Vegfr2 |  | 85 ± 5 | 82 ± 4 |
Icam1 |  | 215 ± 6 | 215 ± 8 |
Icam2 |  | 89 ± 10 | 93 ± 7 |
Vcam1 |  | 38 ± 1 | 36 ± 1 |
Cxcl12 | ↓ | 77 ± 5 | 61 ± 2 |
Cxcr2 | ↓ | 7.0 ± 0.6 | 4.7 ± 0.2 |
Cxcr3 | ↑ | 0.94 ± 0.18 | 1.77 ± 0.20 |
Cxcr4 |  | 24.5 ± 1.6 | 23.1 ± 0.5 |