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Table 2 RNA-seq of lung tissue in WT and Angpt1 Δ/Δ mice

From: Angiopoietin-1 deficiency increases tumor metastasis in mice

Gene Sign.
Change
WT Angpt1KO
Angpt1 22.0 ± 6.2 0.5 ± 0.1
Angpt2   16.6 ± 0.5 14.4 ± 2.1
Angpt4   0.4 ± 0.09 0.5 ± 0.11
Angpl1/Angpt3   1.6 ± 0.15 1.7 ± 0.72
Angptl2   35.8 ± 2.7 34.0 ± 0.9
Angptl3   0.9 ± 0.4 0.8 ± 0.1
Angptl4   8.7 ± 0.4 13.9 ± 2.0
Angptl6   1.2 ± 0.4 1.8 ± 0.3
Angptl7   1.2 ± 0.3 1.5 ± 0.5
Tek/Tie2   144 ± 12 130 ± 4
Tie1   57 ± 2 57 ± 4
Vegfa   437 ± 47 509 ± 39
Kdr/Vegfr2   138 ± 8 146 ± 2
Flt/Vegfr2   85 ± 5 82 ± 4
Icam1   215 ± 6 215 ± 8
Icam2   89 ± 10 93 ± 7
Vcam1   38 ± 1 36 ± 1
Cxcl12 77 ± 5 61 ± 2
Cxcr2 7.0 ± 0.6 4.7 ± 0.2
Cxcr3 0.94 ± 0.18 1.77 ± 0.20
Cxcr4   24.5 ± 1.6 23.1 ± 0.5
  1. An extract of data from RNA sequencing performed on lung tissue from adult WT mice (n = 3) and Angpt1 Δ/Δ mice (n = 4). Data are expressed as average FPKM ± SEM. Arrows indicate significant differences up (↑) or down (↓) compared to WT