Table 3 Adverse events (all grades, occurring in >10% of patients). Total number of patients N = 25
Grade | ||||||
|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | All | ||
N | N | N | N | N | % | |
Fatigue | 6 | 6 | 1 | 0 | 13 | 52.0 |
Hypertension | 4 | 6 | 2 | 0 | 12 | 48.0 |
Anorexia | 8 | 3 | 0 | 0 | 11 | 44.0 |
Nausea | 11 | 0 | 0 | 0 | 11 | 44.0 |
Asthenia | 6 | 4 | 0 | 0 | 10 | 40.0 |
Diarrhea | 8 | 1 | 1 | 0 | 10 | 40.0 |
Dysphonia | 10 | 0 | 0 | 0 | 10 | 40.0 |
Vomiting | 7 | 2 | 1 | 0 | 10 | 40.0 |
Thrombocytopenia | 3 | 2 | 3 | 0 | 8 | 32.0 |
Headache | 6 | 0 | 0 | 0 | 6 | 24.0 |
Abdominal pain | 2 | 2 | 2 | 0 | 6 | 24.0 |
Dysgeusia | 4 | 2 | 0 | 0 | 6 | 24.0 |
Myalgia | 5 | 1 | 0 | 0 | 6 | 24.0 |
Neck pain | 4 | 1 | 0 | 0 | 5 | 20.0 |
Hypothyroidism | 3 | 2 | 0 | 0 | 5 | 20.0 |
Proteinuria | 0 | 3 | 2 | 0 | 5 | 20.0 |
Dry skin | 4 | 1 | 0 | 0 | 5 | 20.0 |
Arthralgia | 3 | 1 | 0 | 0 | 4 | 16.0 |
Elevated bilirubin | 0 | 4 | 0 | 0 | 4 | 16.0 |
Muscular contractures | 4 | 0 | 0 | 0 | 4 | 16.0 |
Hair modified color | 4 | 0 | 0 | 0 | 4 | 16.0 |
Epistaxis | 4 | 0 | 0 | 0 | 4 | 16.0 |
Hemorrhoids | 3 | 1 | 0 | 0 | 4 | 16.0 |
Microangiopathy | 0 | 0 | 4 | 0 | 4 | 16.0 |
Paresthesia | 4 | 0 | 0 | 0 | 4 | 16.0 |
Stomatitis | 2 | 2 | 0 | 0 | 4 | 16.0 |
Hand & foot syndrome | 3 | 0 | 1 | 0 | 4 | 16.0 |
Mucositis | 3 | 1 | 0 | 0 | 4 | 16.0 |
Elevated AST | 2 | 1 | 0 | 0 | 3 | 12.0 |
Back pain | 2 | 1 | 0 | 0 | 3 | 12.0 |
Musculoskeletal pain | 2 | 1 | 0 | 0 | 3 | 12.0 |
Thoracic musculoskeletal pain | 0 | 1 | 2 | 0 | 3 | 12.0 |
Dyspnea | 3 | 0 | 0 | 0 | 3 | 12.0 |
Urinary tract infection | 0 | 3 | 0 | 0 | 3 | 12.0 |
Neutropenia | 0 | 3 | 0 | 0 | 3 | 12.0 |