Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

Peer Review reports

Original Submission
31 Aug 2016	Submitted	Original manuscript
6 Oct 2016	Author responded	Author comments - Stine Winther
Resubmission - Version 2
6 Oct 2016	Submitted	Manuscript version 2
23 Dec 2016	Reviewed	Reviewer Report - David Hsu
28 Dec 2016	Reviewed	Reviewer Report - Van Morris
20 Feb 2017	Reviewed	Reviewer Report - Thomas Aparicio
31 Mar 2017	Author responded	Author comments - Stine Winther
Resubmission - Version 3
31 Mar 2017	Submitted	Manuscript version 3
13 Apr 2017	Reviewed	Reviewer Report - Thomas Aparicio
19 Apr 2017	Reviewed	Reviewer Report - Van Morris
20 Apr 2017	Reviewed	Reviewer Report - David Hsu
24 Jul 2017	Author responded	Author comments - Stine Winther
Resubmission - Version 4
24 Jul 2017	Submitted	Manuscript version 4
27 Jul 2017	Author responded	Author comments - Stine Winther
Resubmission - Version 5
27 Jul 2017	Submitted	Manuscript version 5
Publishing
1 Aug 2017	Editorially accepted
16 Aug 2017	Article published	10.1186/s12885-017-3526-8

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