Fig. 4
From: Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification
Precision medicine approach. A strategy for the application of the individualized medicine that integrates genomic profiling of a patient tumor sample, with patient-derived xenograft (PDX) and PDX cell testings, is depicted here. The genomic profiling of patient tumor samples may lead to the identification of many potential therapeutic targets. The PDX cell model can be used to test these potential drug targets, in order to determine potential therapeutic regimens for any given patient