Table 2 Chemotherapeutical regimens for use during the primary period

Cisplatin/Capecitabine

EOX/EOF

 • Cisplatin 80 mg/m², day 1

 • Capecitabine 1000 mg/m² twice daily on day 1–14

 Each cycle is repeated on day 22.

• Epirubicin 50 mg/m², day 1

• Oxaliplatin 130 mg/m², day 1

• Capecitabine 625 mg/m² twice daily day 1–21 or 5-FU 200 mg/m²/day, continuously day 1–21

Each cycle is repeated on day 22

Cisplatin/S-1

FLOT

 • Cisplatin 75 mg/m², day 1

 • S-1 25 mg/m², twice daily day 1–21

 Each cycle is repeated on day 29.

• Docetaxel 50 mg/m², day 1

• Oxaliplatin 85 mg/m², day 1

• Leucovorin 200 mg/mg², day 1

• 5-FU 2600 mg/m² (24-h infusion), day 1

Each cycle is repeated on day 15

Cisplatin/5-FU

 • Cisplatin 75 (−100) mg/m², day 1

 • 5-FU 800 (−1000) mg/m²/day continuously day 1 to 5 or 1000 mg/m²/day cont. day 1–4

 Each cycle is repeated on day 22

FLO

 • Oxaliplatin 85 mg/m², day 1

 • Leucovorin 200 mg/m², day 1

 • 5-FU 2600 mg/m² (24-h infusion), day 1

 Each cycle is repeated on day 15

Mod. Folfox-6

 • Oxaliplatin 85 mg/m², day 1

 • Leucovorin 400 mg/m², day 1

 • 5-FU 400 mg/m² (bolus), day 1

 • 5-FU 2400 mg/m² (46-h infusion), day 1

 Each cycle is repeated on day 15