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Table 1 Histological and immunohistochemical differences of uterine body tumors

From: Vaginal metastasis as the initial presentation of leiomyosarcoma: a case report

 

Uterine leiomyosarco

Endometrial stromal sarcoma

Smooth muscle tumors of uncertain malignant potential

Leiomyoma

Mitotic rate

>10MF/10HPF

Variable

<10MF/10HPF

<5MF/10HPF

Cell necrosis

Coagulative

Ischemic

Ischemic

Absent or Ischemic

Citological atypia

Frequent

Present

Present

Citologically bland

Vimentin

+

+

+

+

Actin

+

+

+

Desmin

++

+

+

Caldesmon

++

+

+

CD10

++

  1. The following scale was used for staining reaction: - no staining
  2. MF mitotic figures, HPF High power field
  3. + 1% to 25%, ++ 26% to 50%, and +++ 50% of the tumor cells stain positive