Skip to main content

Table 2 Comparison of apoptosis induced by DZNep in chondrosarcomas cultured in 2D and 3D cultures

From: Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

 

Apoptotic cell fraction

p-value (DZNep Vs control)

p-value (DZNep 3D Vs DZNep 2D)

Control

DZNep

2D

0.73 ± 0.3%

29.6 ± 1.4%

0.001

 

3D

21.7 ± 1.4%

86.8 ± 1.7%

0.001

0.001

  1. Chondrosarcoma cells were cultured in monolayer (2D) or embedded in alginate (3D). Then, cells were treated with 1 μM DZNep. Fourteen days later, apoptosis was assayed. Values represent means ± SEM of 3 experiments
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us