Elevated serum CEA levels are associated with the explosive progression of lung adenocarcinoma harboring EGFR mutations

Table 2 Analysis of EFGR mutation

Clinical Characteristic	Sample(n)	EGFR mutation(n)	χ2	P
Gender
Female	92	47	3.957	0.047
Male	63	22		0.047
Age
< 59	74	30	4.230	0.040
≧59	81	39		0.040
Stage
I,II	57	21	2.150	0.143
III,IV	98	48		0.143
PS Score
0-1	152	68	0.155	0.694
2-3	3	1		0.694
Smoker
Ever	63	22	3.957	0.047
Never	92	47		0.047
CEA
< 3.4 ng/ml	63	21	5.374	0.020
≧3.4 ng/ml	92	48		0.020
Cyfra21-1
< 3.3 ng/ml	64	44	25.920	0.001
≧3.3 ng/ml	91	25		0.001

A single factor χ² test showed that EGFR mutation was associated with gender, age, smoking history, and the serological levels of CEA and CYFRA 21-1

ISSN: 1471-2407