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Table 2 Associations between JMJD2A, LDHA protein expression and clinicopathological characteristics in NPC

From: JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression

Variable Cases JMJD2A expression P-value LDHA expression P-value
Low (n = 24) High (n = 26) Low (n = 21) High (n = 29)
Gender
 Male 22 10 12 0.749 9 13 0.890
 Female 28 14 14   12 16  
Age(years)
 < 50 21 9 12 0.536 7 14 0.291
 ≥ 50 29 15 14   14 15  
Histological type
 DNKC 25 11 14 0.571 10 15 0.774
 UDC 25 13 12   11 14  
T classification
 T1-T2 31 20 11 0.003* 18 13 0.003*
 T3-T4 19 4 15   3 16  
N classification
 N0-N1 32 14 18 0.423 13 19 0.793
 N2-N3 18 10 8   8 10  
M classification
 M0 37 21 16 0.037* 19 18 0.024*
 M1 13 3 10   2 11  
Clinical stage
 I-II 24 17 7 0.002* 16 8 0.001*
 III-IV 26 7 19   5 21  
  1. DNKC differentiated non-keratinizing carcinoma, UDC undifferentiated carcinoma, T tumor size, N lymph node metastasis, M distant metastasis
  2. *P < 0.05 indicates a significant association among the variables (2-tailed)