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Table 4 The most discriminative peaks (m/z signals) according to Wilcoxon test (p-values), ROC curve (AUC) and mathematical model (SNN) with their identification

From: MALDI-TOF-MS analysis in discovery and identification of serum proteomic patterns of ovarian cancer

Mass (m/z)

p-value

AUC

Peptide sequence

Identification

Ref.

1505.24

0.00937

0.676

G.SPMYSIITPNILR.L

CO3_HUMAN

[22, 24, 34, 35]

1945.38

0.00290

0.725

H.NLGHGHKHERDQGHGHQ.R

KNG1_HUMAN

[36,37,38,39,40]

2023.17

0.01280

0.667

R.SSKITHRIHWESASLLR.S

CO3_HUMAN

[22, 24, 34, 35]

2082.73

0.00056

0.767

P.GVLSSRQLGLPGPPDVPDHAA.Y

ITIH4_HUMAN

[37, 41,42,43,44,45]

2116.08

0.00171

0.736

Hypothetical

TSSTSYNRGDSTFESKSY

Hypothetical FIBA_HUMAN

-

2210.80

0.00056

0.777

G.ISPFHEHAEVVFTANDSGPR.R

TTHY_HUMAN

[9, 46,47,48]

3158.75

0.00171

0.738

R.NVHSGSTFFKYYLQGAKIPKPEASFSPR.R

ITIH4_HUMAN

[37, 41,42,43,44,45]

6560.82

0.00689

0.680

-

-

-

7567.69

0.01180

0.671

-

-

-

7830.60

0.00451

0.700

-

-

-