Table 3 Univariate and multivariate analyses for DFS
Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|
Variables | HR | 95% CI | P-value | HR | 95% CI | P-value | |
Age | < 65 | 1 | reference | 0.969 | 1 | reference | 0.722 |
≥ 65 | 0.991 | 0.628∼1.564 | 1.092 | 0.672 ~ 1.775 | |||
Sex | Male | 1 | reference | 0.060 | 1 | reference | 0.055 |
Female | 0.608 | 0.362 ~ 1.021 | 0.460 | 0.208 ~ 1.018 | |||
Smoking status | None | 1 | reference | 0.106 | 1 | reference | 0.586 |
Ex-smoker | 2.112 | 1.164∼3.831 | 1.250 | 0.560 ~ 2.794 | |||
Current smoker | 1.35 | 0.775∼2.353 | 0.720 | 0.328 ~ 1.580 | |||
MRS overexpression | Negative/Trace | 1 | reference | 0.017 | 1 | reference | 0.064 |
Positive | 2.33 | 1.161 ~ 4.677 | 2.017 | 0.985 ~ 4.130 | |||
pStage | I | 1 | reference | <0.001 | 1 | reference | < 0.001 |
II | 2.412 | 1.393∼4.175 | 2.547 | 1.349 ~ 4.807 | |||
III | 3.141 | 1.817–5.429 | 2.744 | 1.537 ~ 4.899 | |||
IV | 32.208 | 7.206–143.957 | 26.047 | 5.192 ~ 130.68 | |||
Histologic differentiation | Well | 1 | reference | 0.415 | 1 | reference | 0.687 |
Moderate | 1.767 | 0.904–3.454 | 1.150 | 0.555 ~ 2.383 | |||
Poor | 1.628 | 0.734–3.034 | 1.003 | 0.450 ~ 2.235 | |||