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Table 3 Univariate and multivariate analyses for DFS

From: Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer

   Univariate analysis Multivariate analysis
Variables   HR 95% CI P-value HR 95% CI P-value
Age < 65 1 reference 0.969 1 reference 0.722
≥ 65 0.991 0.6281.564   1.092 0.672 ~ 1.775  
Sex Male 1 reference 0.060 1 reference 0.055
Female 0.608 0.362 ~ 1.021   0.460 0.208 ~ 1.018  
Smoking status None 1 reference 0.106 1 reference 0.586
Ex-smoker 2.112 1.1643.831   1.250 0.560 ~ 2.794  
Current smoker 1.35 0.7752.353   0.720 0.328 ~ 1.580  
MRS overexpression Negative/Trace 1 reference 0.017 1 reference 0.064
Positive 2.33 1.161 ~ 4.677   2.017 0.985 ~ 4.130  
pStage I 1 reference <0.001 1 reference < 0.001
II 2.412 1.3934.175   2.547 1.349 ~ 4.807  
III 3.141 1.817–5.429   2.744 1.537 ~ 4.899  
IV 32.208 7.206–143.957   26.047 5.192 ~ 130.68  
Histologic differentiation Well 1 reference 0.415 1 reference 0.687
Moderate 1.767 0.904–3.454   1.150 0.555 ~ 2.383  
Poor 1.628 0.734–3.034   1.003 0.450 ~ 2.235