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Fig. 1 | BMC Cancer

Fig. 1

From: Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer

Fig. 1

Expression of MRS, Ki67, and, mTOR signaling proteins in the wild type mouse organs. The expression of MRS, Ki67, pS6 (Ser235/236), and pGSK-3β (Ser9) was evaluated by IHC in tissue samples from 8-week-old wild type C57BL/6 mice. pS6 (Ser235/236) and pGSK-3β (Ser9) are surrogate markers of mTORC1 and mTORC2 activity, respectively. IHC analysis revealed that the enterocytes in the intestinal mucosal epithelium and the splenocytes in the periphery of the germinal center expressed MRS, whereas all other organs exhibited weak MRS expression. Photo was taken at low power magnification (X100)

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BMC Cancer

ISSN: 1471-2407

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