Fig. 1

RNF139 regulates the viability, colony formation and invasion of tongue cancer SCC9 and SCC25 cells. a Overexpression of RNF139 inhibits the viability of SCC9 and SCC25 cells. N = 6. b Knockdown of RNF139 promotes the viability of SCC9 and SCC25 cells. N = 6. c Overexpression of RNF139 inhibited the colony formation ability of SCC9 and SCC25 cells. N = 3. d Knockdown of RNF139 promoted the invasion of SCC9 and SCC25 cells. The gel/blots which indicates the efficiency of RNF139 overexpression were the same gel/blots in (a) and (c). The gel/blots which indicates the efficiency of RNF139 knockdown were the same gel/blots in (b) and (d). N = 3. *:P < 0.05, **:P < 0.01